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10th International Conference on Depression, Anxiety and Stress Management

Berlin, Germany

Elsayed Abed

Al-Azhar University, Egypt

Title: Relation of post-stroke headache to cerebrovascular pathology and hemodynamics

Biography

Biography: Elsayed Abed

Abstract

Background: Despite the high prevalence of cerebrovascular stroke, headache attributed to ischemic strokes is often undertreated and overlooked. The aim is to detect the relation of a post-stroke headache to cerebrovascular pathology and changes in hemodynamics through a high-resolution duplex ultrasound examination.

Methods: This is a prospective case-control study that was conducted in Kasralainy hospital, Cairo University and Al-Azhar University hospitals from January 2021 to August 2021.The study was  conducted on 239 patients who presented with an acute ischemic stroke. Patients were subdivided into two groups; Group I included patients with headache attributed to ischemic stroke (cases) and Group II included headache-free stroke patients (controls). History included headache characteristics and risk factors. Clinical and radiological examination was performed to detect the type of stroke. Ultrasound duplex examination of the extra cranial and intracranial cerebrovascular system was carried for both groups.

Results: Group I included 112 patients (mean age 57.66 ±6.59 years), Group II included 127 patients (mean age 57.73±7.89 years). Post-stroke headache was more frequent in patients with posterior circulation infarction (58%). Post-stroke headache was reported within 7 days post-stroke in (61.6%) of patients. Pre-stroke headache was an independent predictor for post-stroke headache occurrence (OR=28.187, 95%CI; 6.612-120.158, P<0.001). Collateral opening and various degrees of intracranial vascular stenosis were strong predictors of headache occurrence (OR=25.071, 95% CI; 6.498-96.722, P<0.001).

Conclusion: Post-stroke-headache is a common phenomenon especially in patients with pre-stroke headache, history of old stroke, posterior circulation infarction, and large artery disease. This headache was of moderate-intensity with clinical characteristics of tension-type. The intracranial cerebrovascular pathological changes including opening of the collateral channels and variable degrees of stenosis of cerebrovascular systems were implicated in the production of that headache.

Keywords: Post-stroke headache; Cerebrovascular; Hemodynamics; Duplex ultrasound.