Day 2 :
JFK Medical Center, USA
Keynote: The impact of the MAP (Mindfulness Attention Program) on Neurologic symptoms associated with Brain Injury (BI)
Time : 10:00-10:45
Joanne Azulay is clinical Neuropsychologist and Researcher at the JFK Johnson Rehabilitation Institute- USA and is an Assistant Clinical Professor of Physical Medicine and Rehabilitation at Robert Wood Johnson Medical School/ Rutgers University and Neuroscience at Seton Hall University. Dr. Azulay received her doctoral training in Clinical Psychology from Seton Hall University, completed her residency at UMDNJ Robert Wood Johnson Medical School. Dr. Azulay has been treating and researching in the field of neurologic disorders with a specialty in cognitive disorders of concussion. She has studied meditation in the Tibetan tradition as well as MBSR. Bringing together her training in mental health, brain injury and meditation, Dr. Azulay has been lecturing, publishing and teaching nationally and internationally for both patients and non-patients alike
Objective: To introduce a mindfulness meditation treatment program called the Mindfulness Attention Program (MAP). This program was developed and researched to address neurologic symptoms and has been running successfully for over ten years to address memory, attention and self-regulation deficits associated with neurologic disorders such as TBI, Stroke, Parkinson's, and Autoimmune disorders.
Design: Over the last six years we have assessed a convenience sample in a post acute brain injury rehabilitation center. Participants completed outcome measures and neuropsychological testing pre and post treatment intervention.
Participants: Participants included sixty- eight individuals with neurologic disorders and a time post onset greater than 7 months.
Intervention: The intervention consisted of a 10-week group (with weekly, 2-hour sessions) mindfulness program designed to facilitate implementation with a neurologic population. The treatment-involved the enhancement of attentional skills, increased awareness of internal and external experiences and exploration of physical and emotional pain.
Main Outcome Measures: Primary outcome measures included the Perceived Quality of Life Scale (PQOL), Perceived Self-Efficacy Scale (PSE) and the Neurobehavioral Symptom Inventory (NSI). Additional measures included neuropsychological (NP) tests, a self –report problem solving inventory, an emotional regulation measure and self-report measure of mindfulness.
Results: Clinically meaningful improvements were noted on measures of quality of life (Cohen’s d = 0.53) perceived self-efficacy (Cohen’s d = 0.57), and emotional regulation (Cohen’s d = 0.70), with smaller but still significant effects on measures of central-executive aspects of working memory.
Conclusion: A modified mindfulness program called the MAP is a powerful intervention with the cognitive, emotional and physical symptoms associated with a neurologic population.
Chiangmai University, Thailand
Time : 11:15-12:00
Background: Informal sector is one of the important industries employing a large number of people on its workforce, especially in the developing country like Thailand. The workers in the informal sector suffer from various types of occupational risks and musculoskeletal pain (MSP). Ergonomic risks and mental agony are recognized as important in the development and progression of MSP that can result in potentially huge cost in terms of health problems and economic burden for the individual and society. This study aimed to focus on the association among ergonomic risks, mental agony and MSP as well as discusses potential solution and recommended practices for minimizing the negative ergonomic and psychological consequences of the Thai informal sector.
Method: Total of 979 home-based handicraft workers were invited to participate in the study; 174 workers gave incomplete responses resulting a final response rate of 82.23%. The analysis sample comprised of 805 workers including ten groups of handicraft profession in Chiangmai and Lumpun provinces, Thailand. Research instruments were consisted of an interview questionnaire and the ergonomic checklist. The three levels of MSP participants were compared using chi-square test. Multiple regression analyses evaluated the significant impacts of independent variables on the dependent variable.
Results: The overall prevalence of MSP in the Thai home-based handicraft workers was 96.5%. The most common location for MSP was upper back (86.8%). Poor work methods was found to be a highest prevalence for ergonomic risks (100%) while burnout was found to be a highest prevalence of mental risk (97.2%). Analysis with the chi-square test indicated significant differences between mental agony and ergonomic (except work method) risks for the three levels of MSP (P<0.001). The analysis with multiple regression suggested mental risks were more important than ergonomic risks in explaining variations in MSP. Workstation design (β =0.087, t=2.475 p<0.05) and work methods (β =0.087, t=2.190 p<0.05) were the most significant ergonomic risk factors while burnout (β =0.313, t=6.273 p<0.001) was the strongest mental risk factor impacting the severity of MSP. The model explained 16.3 of the variance for MSP severity. On the other hand, anxiety (β =0.704, t=26.246 p<0.001) and work methods (β =0.085, t=3.177 p<0.01) were the significant risk factors impacting the severity of burnout. The model explained 51.8% of the variance in burnout severity.
Conclusions: The Thai informal sector is a high risk occupational sector to develop various types of MSP. The prevalence of MSP is very high. Both ergonomic risks and mental agony have significant impacts. To prevent MSP, an interdisciplinary and a multi-level approaches are needed, MSP and occupational risk assessment should be conducted from time to time. If significant risk factors are observed, appropriate interventions and management should be taken. Thai government should push more active political agendas and action frameworks for reducing MSP, mental agony and unorganized surroundings derived from informal employment.
- Depression and Anxiety | Stress and Behavoir
Chiangmai University, Thailand
UNIFESP-Escola Paulista de Medicina, Brazil
Time : 12:40-13:10
Bergantin received his academic education at UNIFESP-EPM (Brazil) and UAM (Spain): degree in biomedicine (2008), MSc (2010) and PhD (2014). His research involves cell signaling mediated by Ca2+ and cAMP, skeletal and smooth muscles, peripheral and central nervous systems. His research work solved the enigma of the paradoxical effects produced by L-type Ca2+ channel blockers (ScienceDirect TOP 25 Hottest Articles, including TOP 1 positions: 2013 and 2014, Cell Calcium)
The hypothesis of the so-called “calcium paradox” phenomenon in the sympathetic neurotransmission has its origin in experiments done in models of neurotransmission since 1970´s. Historically, “calcium paradox” originated several clinical studies reporting that acute and chronic administration of L-type Ca2+ Channel Blockers (CCBs), drugs largely used for antihypertensive therapy such as verapamil and nifedipine, produces reduction in peripheral vascular resistance and arterial pressure, associated with a paradoxical sympathetic hyperactivity. Despite this sympathetic hyperactivity has been initially attributed to adjust reflex of arterial pressure, the cellular and molecular mechanisms involved in this paradoxical effect of the L-type CCBs remained unclear for four decades. Also, experimental studies using isolated tissues richly innervated by sympathetic nerves showed that neurogenic responses were completely inhibited by L-type CCBs in high concentrations, but paradoxically potentiated in low concentrations, characterized as a “calcium paradox” phenomenon. We discovered in 2013 that this paradoxical increase in sympathetic activity produced by L-type CCBs is due to Ca2+/cAMP interaction (Bergantin et al., Cell Calcium, 2013; ScienceDirect TOP 25 Hottest Articles - Cell Calcium - TOP 1 July to September 2013/ TOP 5 October to December 2013/ TOP 1 January to December 2013 full year/TOP 6 January to March 2014). Then, the pharmacological manipulation of this interaction could represent a potential cardiovascular risk for hypertensive patients due to increase of sympathetic hyperactivity. In contrast, this pharmacological manipulation could be a new therapeutic strategy for increasing neurotransmission in psychiatric disorders such as depression (Caricati-Neto et al. 2015, Pharmacol Res Perspectives; Bergantin and Caricati-Neto 2016, Eur J Pharmacol).
Cairo University, Egypt
Time : 13:15-14:20
Ahmed Fathy Al kady has completed his Master studies at the age of 28 years from Cairo University , faculty of Nursing. He is assistant lecturer at faculty of Nursing , Cairo University . He has published 2 papers in national journals . he had a bachelor degree in nursing with excellent degree with honor degree.
Coronary angiography is a widespread invasive procedure used for management of coronary artery diseases and heart valve diseases. The aim of the study was to assess the patient preferences of anxiety reducing strategies prior to coronary angiography. The research question was what are the patient preferences of anxiety reducing strategies prior to coronary angiography? Research design: A descriptive exploratory design was utilized to fulfill the aim of the study. A convenient sample consisted of 60 adult patients undergoing coronary angiography at one of Cairo University hospitals, Egypt. Three tools were used to collect data pertinent to the study: a) Semi-structured interview questionnaire to assess the subjects’ socio-demographic and medical related variables data , b) Numeric Visual Analog Anxiety Scale (NVAAS) to assess level of anxiety and c) the anxiety reducing strategies questionnaire used to assess subjects’ preferences of anxiety reducing strategies prior to coronary angiography. More than half of the study subjects had moderate to severe anxiety (53%).The study subjects preferred supplication, prayer and listening and recitation of Quran to control their anxiety before Coronary angiography. In-service training programs should be planned and applied frequently to all nurses to boost their knowledge and practice regarding patient’s psychological status especially before coronary angiography procedure.
Heidelberg University, Germany
Time : 14:10-14:40
Pediatric Clinical Hospital, Romania Panel Discussion
Title: Influence of "Antiaging+Antioxidant" product on the oxidative stress of third molar extraction
Time : 12:30-13:00
Training. MD, bachelors of Psychology, Pedagogical education, PhD student.
Professional activity. Teaching in Romanian and French, at Chair of Pathophysiology, „Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca Romania. Medical practice in private area.
Professional experiences. Researches in the field of surgical, physical, psycho-emotional and oxidative stress and non-conventional medicines. Participation in scientific events of Pathophysiology, Physiology, Psycho-Neuro-Endocrinology, Stress, Psychology, Non-conventional Medicines.
Skills. English, French, Italian and Spanish. Use of PC. Scientific instrumentation. Enthusiasm, flexibility, creativity, organizational capacity, tolerance, team spirit.
Background. It was proven that some herbs have antioxidant effects, but less is known about the antioxidant effect of some plants combinations, in the third molar extraction.
Objectives. The objective of the study was to evaluate the influence of "Antiaging+Antioxidant " (PAA) product on oxidative stress of third molar extraction.
Methods. Selected subjects (N=24), with the indication of the third molar extraction, were randomly divided in three groups: control (C=8) without treatment; who received PAA 21 days (AA21=8); and who received PAA 42 days (AA42=8) before the third molar extraction. The analyzed indicators were glutathione peroxidase (GPO) and malondialdehyde (MDA).
Results. Following PAA therapy, GPO and MDA were significantly reduced compared to C: most intense after AA42 (p = 0.03 for GPO and p = 0.01 for MDA) than after AA21 (p = 0.05 for GPO and p = 0.05 for MDA ). Difference between PAA21, respectively PAA42 influence on GPO and MDA was not significant. Differences between AA21 and AA42 were significantly reduced for GPO (p = 0.05) and MDA (p = 0.05).
Conclusions. 1) Under the influence of PAA, GPO and MDA were significantly reduced, more intensively for AA42 compared to AA21. 2) PAA action on GPO and MDA was similar. 3) The PAA influence on GPO and MDA was increased after surgery. 4) We consider that the use of PAA, especially that 42, might be useful in the extraction of third molar intervention, by modulating the oxidative stress effect.
Key words: oxidative stress, glutathione peroxidase, malondialdehyde, third molar extraction